Role of sodium tungstate as a potential antiplatelet agent

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Role of sodium tungstate as a potential antiplatelet agent

PURPOSE Platelet inhibition is a key strategy in the management of atherothrombosis. However, the large variability in response to current strategies leads to the search for alternative inhibitors. The antiplatelet effect of the inorganic salt sodium tungstate (Na2O4W), a protein tyrosine phosphatase 1B (PTP1B) inhibitor, has been investigated in this study. METHODS Wild-type (WT) and PTP1B k...

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ژورنال

عنوان ژورنال: Drug Design, Development and Therapy

سال: 2015

ISSN: 1177-8881

DOI: 10.2147/dddt.s77221